What Are the Dangers of Pycnogenol? | Live Healthy - Chron Systolic blood pressure measures how much blood is pumping from your heart to your arteries. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. In combination with Mirtoselect, Pycnogenol may improve blood flow to the eye and reduce eye blood pressure as shown in a trial of 38 people [81]. Some small studies suggest it may also protect against coronary artery disease and blood clots. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Pycnogenol seems well-tolerated for use in adults for up to 6 months. No side effects were noted, unlike its synthetic counterpart. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. 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A 2004 animal study also found that applying a gel containing pine bark extract sped up the wound-healing process. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. The dosage in most clinical studies varied between 50-360 mg/day. Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. As I mentioned, pine bark extract is superior when it comes to antioxidants. With time, the participants were able to handle more UV radiation without experiencing skin damage [63]. This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. You can refer to the National Institutes of Healths dosage guidelines for specific conditions. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. Consequently, blood pressure is lowered. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. Pycnogenol can help control blood pressure, which helps improve overall heart health. More research is needed to see how this supplement affects all of these conditions. Pycnogenol Benefits, Dosage & Side Effects - Ayur Times Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. Used early on, it may prevent eye damage and blindness from diabetes [34]. (2017). Benefits Of Pycnogenol To Live Longer - Life Extension Pycnogenol has not been found to cause these issues however, it may take a little longer the feel the relief from pain than aspirin. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. SelfDecode is a personalized health report service, According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. Pine bark extract is composed of 80% to 85% proanthocyanidins, the monomers catechin and taxifolin (5%), and phenolic acids, including derivatives of benzoic and cinnamic acids (2% to 4%). In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). Pine Bark Extract Health Benefits, Nutrition and How to Use - Dr. Axe Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [17]. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. What are the Benefits of Taking Beta 1 3D Glucan? - betterwayhealth DOI: Gulati OP. Optimal doses of pycnogenol have not been set for any condition. Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. More specifically, because it strengthens the capillaries in the retina, Mirtogenol can help prevent retinopathy. Set Ascending Direction. The first studied group included 66 healthy subjects in whom the number of muscle cramps was recorded two weeks before entering the study and during the fourth and fifth week. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. Take Helpful Supplements. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. Pycnogenol may help with other conditions as well. Although these may still be high quality, the active compounds are more likely to vary. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . blood in the urine. The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. For asthma in children: 1 milligram per pound of body weight given in two divided doses. 10 Day Erection Delay Sex Pills. It also may enhance swimming, biking, and running scores in professional athletes preparing for a triathlon (at 150 mg/day). 1. High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. She loves communicating science and empowering people to achieve their optimal health. Studies have found that supplementing with pycnogenol effectively strengthens the blood vessels, stabilizing blood pressure. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. Dr. Drew explains the benefits of probiotics for the gut microbiome and talks about the rise of leaky gut, and Dr. Steve shares how emotional stress can have real physical effects on the heart. Potential for allergy when taken orally or used on the skin. It may cause side effects such as: Dizziness. Dr. Eric L. Zielinski is a sought-after natural . The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. A Pycnogenol combination product (with l-arginine, alpha lipoic acid, B vitamins, and vitamin K2) may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [39]. 7 Health Benefits of Pine Bark Extract - Natures Fare But what makes this miracle ingredient so amazing? When pycnogenol cream was added to oral supplements in a small study of 18 people with vein ulcers, it helped ulcers heal more quickly [26]. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. (9), Related:Top 7 Benefits of Green Tea: The No. What Are These Tiny Red Spots on My Skin (Petechiae)? It can then lead to heart problems like stroke or heart attack. Note that the numbers in parentheses (1, 2, etc.) The staff there can often answer any questions you have and give you more information about specific brands. How to Get Rid of Hemorrhoids (4+ Natural Remedies) - Dr. Axe This supplement may also increase muscle endurance and performance after a single pre-exercise dose according to a study of 9 cyclists [12, 13]. The outcome showed significant healing when compared to those subjects who were not given any drug or remedy, concluding that Pycnogenol may be an effective remedy for healing of surgery-related lesions. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. Tell your doctor about any supplements you're taking, even if they're natural. In a study of 50 overweight people, a combination product (Pycnogenol, Madeglucyl, and starches called Glucaffect) reduced weight, BMI, blood glucose, and HbA1C after 8 weeks [30]. Pycnogenol: French maritime pine bark extract It is chronic venous insufficiency, a common disease among people who are obese or elderly and those who lead a sedentary lifestyle. The Benefits of DIM. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. This study adds to a body of research showing the benefits of Pycnogenol . Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. They were treated with 200 mg of Pycnogenol daily or with placebo. Researchers suggest that it may have stronger benefits than elastic compression stockings. Organika Pycnogenol 50mg 50 Tablets . Helps maintain high vitamin C and E blood levels for their antioxidant effects. While OPCs found in this extract are mostly known for their antioxidant-producing benefits, these amazing compounds exude antibacterial, antiviral, anticarcinogenic, anti-aging, anti-inflammatory and anti-allergic properties. Natural Factors Pycnogenol 25mg 60 Veggie Caps. American Cancer Society: "Pine Bark Extract.". Pycnogenol is considered possibly safe when taken orally or when applied topically as a cream or ointment. After taking a break for one to two weeks, they can start taking it again for several weeks. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". Read More: Health Benefits of Peanut Butter. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. Diarrhea. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Pycnogenol was featured on The Dr. Oz Show in January 2013, . The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD) [Abstract]. A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. If you knew you could resolve your erectile dysfunction and, therefore, naturally remedy impotence issues, wouldnt you? Boost gastrointestinal health. However, its always a good idea to start with a low dose so you can monitor how your body responds. Another one of its exemplary effects is helping manage blood pressure levels. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. They include: We need more research to know for sure if pycnogenol helps treat these conditions. Pycnogenol and Pine Bark Extract Supplements. Learn more about how to get even skin tone. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. Our goal is to not have a single piece of inaccurate information on this website. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. Importantly, all studies found that Pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it 7-8 weeks ahead. WebMD does not provide medical advice, diagnosis or treatment. Studies have been conducted to review the effects of pine bark extract on pseudomonas infectious wounds. Considering that about 1 of 3 adults in the U . Prenatal nutrition can be confusing. Pycnogenol, French Maritime Pine Bark Extract, 100 mg, 60 caps - Life Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. There havent been any studies looking at long-term liver damage. Note that the numbers in parentheses (1, 2, etc.) We do not aim to diagnose, treat, cure or prevent any illness or disease. Learn more. (2006). The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. In a study of 61 ADHD children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. Helps Increase Athletic Performance. Some research suggests that procyanidins may have antioxidant and anti-inflammatory activity. 1) Encourages Healthy Blood Pressure. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. In this study, 155 peri-menopausal women were enrolled in a double-blind, placebo-controlled study. There are also several other natural ADHD remedies you can try. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Pycnogenol is the US trademarked name for an antioxidant made from Mediterranean tree bark. It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. We believe that the most accurate information is found directly in the scientific source. Note that each number in parentheses [1, 2, 3, etc.] Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. In a study of 72 children undergoing cancer chemotherapy, Pycnogenol reduced painful mouth ulcers, both alone and in combination with vitamin E [79]. Some people seek to manage ADHD symptoms through an ADHD diet. In a double-blind, placebo-controlled, randomized, crossover study, 50 patients with erectile dysfunction (ED) were treated with either L-arginine plus Pycnogenol or placebo for a month. DOI: Chowdhury WK, et al. Pycnogenol Review - Worlds Best Anti-Aging Supplement?
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